Cell Optimization

A world-class platform from host selection to cell and process optimization

Advantaged production hosts

Beginning design with the end in mind

Mammalian

Massive cell engineering experience
Traditional systems experience (e.g. CHO)
iPSCs and primary hematopoietic cells

Viral

Bacteriophage engineering
Mammalian viruses
Synthetic modular genomes

Heterotrophic

Fungal like properties; fast growth
High capacity for lipid production
Proprietary biologics production platform

Phototrophic

Long term low cost production platform
Optimized fatty acid biosynthesis
Bench to production scale

Synthetic

Bottom-up genome construction to build for purpose
Genome scale design and optimization

System optimization

Proprietary ‘omics tools
Evolutionary adaptation
Elucidating metabolism
Overproducing precursors
Maximizing pathway fluxes

Process customization

Scale-up and scale-down process development

Selection, evolution and optimization to fit the product

Vaccines
Biologics
Bio-based chemicals
Nutritional supplements

Targeted medicines
Sustainable fuels
Quality foods
Transplantable organs